Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1075 | Thyroid (non-cancer) | ECE2013

Protective antioxidative effects of caffeic acid phenethyl ester in the thyroid and the liver are similar to those caused by melatonin

Kokoszko-Bilska Agnieszka , Stepniak Jan , Lewinski Andrzej , Karbownik-Lewinska Malgorzata

Whereas oxidative reactions occur in all tissues and organs, the thyroid gland constitutes such an organ, in which oxidative processes are indispensable for physiological functions. Thus, with additional oxidative abuse caused by several factors, increased oxidative damage to macromolecules may occur in the thyroid. In turn, numerous metabolic reactions occurring in the liver create favourable conditions for huge oxidative stress.Melatonin is a well-know...

ea0022p686 | Obesity | ECE2010

Increased oxidative damage to lipids and DNA in overweight and obese patients

Szosland Janusz , Kokoszko Agnieszka , Zasada Krzysztof , Stepniak Jan , Lewinski Andrzej , Karbownik-Lewinska Malgorzata

Introduction: Obesity does constitute one of the most common modifiable risk factors for cancer. The process of cancerogenesis is associated with the enhanced oxidative stress. Lipid peroxidation (LPO), resulting from oxidative damage to membrane lipids, as well as oxidative damage to DNA, are the most frequently examined processes to evaluate oxidative damage to macromolecules.Aim: The aim of the study was to evaluate the level of oxidative damage to me...